Come and join us at Monash University‘s Faculty of Pharmacy and Pharmaceutical Sciences. We have 2 PhD scholarships available.
The strategy of FBDD involves screening libraries of small chemical compounds or ‘fragments’ that, owing to their size, generally bind with relatively low affinity and then elaborating these to produce larger, higher affinity ligands (or hits). The process of fragment elaboration to generate high-affinity compounds remains one of the major challenges in FBDD. Projects in the CFBD involve research in different aspects of this process and require expertise in one or more of the following areas: medicinal chemistry, structural biology, biophysics, and/or biochemistry.
Current projects involve the development of novel antibacterial and antiviral compounds; development of novel approaches to screening “difficult” targets; development of compounds for the treatment of metabolic disease.
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