The research paper, The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors, was published in Molecules, October 2019. The work takes a fragment-based drug discovery approach to target the thiol-disulfide oxidoreductase enzyme DsbA from Escherichia coli (EcDsbA). It suggests the potential to develop benzofuran fragments into a novel class of EcDsbA inhibitors.

Duncan, L., Wang, G., Ilyichova, O. V., Scanlon, M. J., Heras, B. M., & Abbott, B. The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors. Molecules 2019, 24(20), 3756. https://doi.org/10.3390/molecules24203756